I haven’t bought this bag myself but the React Messenger from Travelon uses a mixture of old and new technology to protect your stuff from sticky fingers – and I don’t mean it wipes clean after someone’s been eating a doughnut.
The bag has an outer skin made from a kind of chainmail which provides a slash-proof layer while the shoulder strap is constructed with an integral cut-proofing like the Pac Safe strap that protects my DSLR. Additionally the main compartment is kept closed by locking carabiners and the whole thing can be locked to a chair or other more immovable object of your choice.
Perfect for protecting your precious tech and/or secret government documents. Just don’t leave it on a train or somewhere.